Reaction or route optimisation approaches are typically applied throughout our discovery programs to develop chemical efficiency.  However, sometimes for late stage projects this can be even more crucial to ensure sufficient materials can be delivered for further studies.

 

Our approach to optimisation encompasses a range of approaches such as Design of Experiment (DoE) software, solid supported reagents and scavengers, as well as flow chemistry applications.  These approaches can be equally applied to chemical libraries, LO projects and early stage development programs.  A package of experimental data is routinely developed which includes analytical traces, DoE analysis and raw experimental from electronic laboratory notebooks.