Sygnature Chemical Services Ltd. and Heptares Therapeutics Ltd., a drug discovery company focused on novel small-molecule drugs targeting G-protein-coupled receptors (GPCRs), today announced that they have entered into a contract chemistry collaboration in drug discovery. Under the terms of the agreement, scientists from the two companies are working together to advance one of Heptares’ internal high-value GPCR programmes. Sygnature is providing synthetic chemistry services to produce a novel chemical library for Heptares to evaluate against purified, stabilised and functional proprietary GPCR targets (known as StaRs™, Stabilised Receptors).

Commenting on the agreement, Dr Simon Hirst, Sygnature’s Chief Executive Officer, said, "We are delighted that Heptares has chosen to collaborate with Sygnature on this programme. Heptares’ decision to work with us demonstrates our growing reputation for delivering ‘top tier’ science coupled with high value and quality."

Dr Miles Congreve, Head of Chemistry at Heptares said, "We are working with Sygnature on this drug discovery programme which forms a component of our efforts to develop novel GPCR-focused therapeutics. Sygnature is becoming well-known and respected within the pharmaceutical industry for its high-quality medicinal and synthetic chemistry driven services.”